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Matchup

Annie
Annie
17%
83%

vs

50.0%
Karma
Karma
11%
89%
Heavy AP damageHeavy shieldingHeavy pokeHeavy CC

You are stronger late game — farm safe and avoid early trades.

Build vs Karma

Build adapted to this matchup

Starting items

Doran's Ring
Health Potion
x2

Core build

Malignance
1Mage
Hextech Rocketbelt
2Mage tank
Zhonya's Hourglass
3vs AD

Standard

Sorcerer's Shoes
4Magic pen
Stormsurge
5vs Tank

Summoner spells

41450%
41231%

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Stormsurge
5vs Tank
Shadowflame
vs Tank
Void Staff
vs Tank

DPS

Rabadon's Deathcap
Mage
Luden's Echo
Mage

Other options

Dark Seal
100.0% WR2 games
DominationDomination
ElectrocuteElectrocute
Cheap ShotCheap Shot
Grisly MementosGrisly Mementos
Relentless HunterRelentless Hunter
SorcerySorcery
Axiom ArcanistAxiom Arcanist
Absolute FocusAbsolute Focus
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
AnnieAnnie
KarmaKarma
Neutral
Neutral
Neutral

Karma's abilities

Passive, spells and ultimate

Gathering Fire (P)

Karma's damaging abilities will reduce the cooldown of Mantra.

Cooldowns

Cooldowns by spell rank

LevelQWER
39s12s10s–
67s12s10s40s
95s12s10s40s
115s12s10s38s
165s12s9s36s
185s12s8s36s

Playing against Karma

How to counter and exploit weaknesses

1

Karma is strong early but scales poorly — she falls off in effectiveness compared to other supports/mages in the late game.

2

Her RQ is her only real burst: dodge it and she has no offensive threat left.

3

W roots after 2s: break the connection by moving away before it triggers.

4

Focus her in teamfights to prevent her from shielding her entire team with RE.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026