Matchup

Evelynn
Evelynn
36%
64%

vs

48.6%

over 251 games

Karthus
Karthus
17%
83%
Heavy AP damageCountered by stasisSustained DPSHigh burst

Skill matchup

Build vs Karthus

Build adapted to this matchup

Starting items

Gustwalker Hatchling
Health Potion

Core build

Dark Seal
1
Stormsurge
2vs Tank
Shadowflame
3vs Tank

Standard

Sorcerer's Shoes
4Magic pen
Lich Bane
5Mage

Summoner spells

41199%
6111%

Anti AD

Plated Steelcaps
4vs AD
Zhonya's Hourglass
5vs AD

Anti AP

Mercury's Treads
4vs CC
Banshee's Veil
5vs AP

Anti Tank

Void Staff
5vs Tank
Cryptbloom
vs Tank

DPS

Lich Bane
Mage
Rabadon's Deathcap
Mage
Hextech Rocketbelt
Mage tank

Other options

Mejai's Soulstealer
100.0% WR3 games
DominationDomination
ElectrocuteElectrocute
Sudden ImpactSudden Impact
Grisly MementosGrisly Mementos
Relentless HunterRelentless Hunter
SorcerySorcery
Absolute FocusAbsolute Focus
Gathering StormGathering Storm
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
EvelynnEvelynn
KarthusKarthus
Aggressive
Careful
Careful

Karthus's abilities

Passive, spells and ultimate

Death Defied (P)

Upon dying, Karthus enters a spirit form that allows him to continue casting spells.

Cooldowns

Cooldowns by spell rank

LevelQWER
30s15s0.5s
60s15s0.5s3m20
90s15s0.5s3m20
110s15s0.5s3m
160s15s0.5s2m40
180s15s0.5s2m40

Playing against Karthus

How to counter and exploit weaknesses

1

Zhonya's, Edge of Night, and Banshee's block/cancel his R — buy one of these items if Karthus focuses you.

2

His Q deals double damage on isolated targets: stay in your minions or near allies to split the damage.

3

Shields, Soraka R, and heals can counter his R if well-timed — save an emergency heal for Requiem.

4

Karthus is immobile and squishy — dive him quickly to eliminate him before he deals continuous damage.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 8, 2026