Gragas vs Garen

Let Barrel Roll (Q) charge before detonating it: damage and slow grow the longer it sits on the ground, and if you don't recast it, it explodes on its own.

Drink Drunken Rage (W) before engaging: drinking takes 1 second, then you take less damage and your next auto hits every nearby enemy.

Engage with Body Slam (E) through a path without minions: you stop on the first enemy you meet, and hitting reduces its cooldown.

After Body Slam (E), cast Explosive Cask (R) behind your target: the blast knocks enemies away from the impact, sending them toward your team.

Hit him regularly, even with a small poke: Perseverance (passive) only regenerates him if he hasn't taken damage recently.

If you're ranged, kite him: his kit has no dash, and only Decisive Strike (Q) speeds him up and removes his slows.

Wait for the Courage (W) shield to end before your burst: the spell starts with a shield and tenacity, then keeps only a damage reduction.

Once he hits level 6, back instead of staying in lane at low health against him: Demacian Justice (R) deals true damage that grows with your missing health.