Recommended Build

Playing as Lillia

Tips to maximize your impact

Hit with the edge of your Q
Hit with the edge of Blooming Blows (Q), not the center: only the outer edge adds true damage.
Stack your speed, then kite
Hit enemies with your spells and keep your distance: Blooming Blows (Q) gives you a stack of move speed on each hit, enough to kite and dodge.
Start with your seed
Start the fight from range with Swirlseed (E): it damages, slows and reveals, and if it hits nothing, it rolls on to the first enemy or wall.
Mark them all before your R
Before Lilting Lullaby (R), hit as many enemies as you can: Dream-Laden Bough (passive) marks every target of your spells, and only marked ones fall asleep.

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Global strengths and weaknesses

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Build, runes and tips against each opponent

How to counter and exploit weaknesses

Hug her or back off from her Q
Against Blooming Blows (Q), stick to her or back out of range: only the outer edge of the zone adds true damage.
Leave the center of her W
Get out of the center of Watch Out! Eep! (W): the zone deals much more damage there than at the edge.
Dodge her spells, seed included
Dodge her spells, even Swirlseed (E), which rolls to the first enemy: each one marks you for Lilting Lullaby (R), which puts every marked enemy to sleep.
Save your CC for her
If you have CC, use it on her: with no dash, she relies on the move speed Blooming Blows (Q) gives her for each spell that hits.