Matchup
Build vs Gwen
Build adapted to this matchup
Starting items
Core build
Standard
Summoner spells
73%
26%Anti AD
Anti Heal
Anti AP
Anti Tank
DPS
Other options
Domination
Electrocute
Cheap Shot
Grisly Mementos
Ultimate Hunter
Sorcery
Transcendence
Manaflow Band
Power Spikes
Strength by game phase
Lissandra
GwenGwen's abilities
Passive, spells and ultimate
Gwen's attacks deal bonus magic damage based on the targets health. She heals for a portion of the damage dealt to champions by this effect.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 6.5s | 22s | 13s | – |
| 6 | 5s | 22s | 13s | 2m |
| 9 | 3.5s | 21s | 13s | 2m |
| 11 | 3.5s | 20s | 13s | 1m40 |
| 16 | 3.5s | 18s | 12s | 1m20 |
| 18 | 3.5s | 18s | 11s | 1m20 |
Playing against Gwen
How to counter and exploit weaknesses
Her W doesn't protect her from attacks inside the zone: step into her mist to fight her.
Gwen is weak in early game (levels 1-4) — punish her before she gets her stacks and first item.
Grievous Wounds reduces her Q sustain (true damage + heal), which is her main survivability.
She's better in 1v1s and split pushing — force teamfights where she's less effective.
Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026