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Matchup

Lissandra
Lissandra
20%
80%

vs

50.0%
Karma
Karma
11%
89%
Heavy AP damageHeavy shieldingHeavy pokeHeavy CC

Build vs Karma

Build adapted to this matchup

Starting items

Doran's Ring
Health Potion
x2

Core build

Luden's Echo
1Mage
Shadowflame
2vs Tank
Zhonya's Hourglass
3vs AD

Standard

Sorcerer's Shoes
4Magic pen
Malignance
5Mage

Summoner spells

41267%
41433%

Anti AP

Mercury's Treads
4vs CC
Banshee's Veil
5vs AP

Anti Tank

Void Staff
5vs Tank
Stormsurge
vs Tank
Cryptbloom
vs Tank

DPS

Malignance
Mage
Rabadon's Deathcap
Mage
Blackfire Torch
Mage
Hextech Rocketbelt
Mage tank

Other options

Dark Seal
Oblivion Orb
100.0% WR2 games
DominationDomination
ElectrocuteElectrocute
Cheap ShotCheap Shot
Grisly MementosGrisly Mementos
Ultimate HunterUltimate Hunter
SorcerySorcery
TranscendenceTranscendence
Manaflow BandManaflow Band
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
LissandraLissandra
KarmaKarma
Neutral
Neutral
Neutral

Karma's abilities

Passive, spells and ultimate

Gathering Fire (P)

Karma's damaging abilities will reduce the cooldown of Mantra.

Cooldowns

Cooldowns by spell rank

LevelQWER
39s12s10s–
67s12s10s40s
95s12s10s40s
115s12s10s38s
165s12s9s36s
185s12s8s36s

Playing against Karma

How to counter and exploit weaknesses

1

Karma is strong early but scales poorly — she falls off in effectiveness compared to other supports/mages in the late game.

2

Her RQ is her only real burst: dodge it and she has no offensive threat left.

3

W roots after 2s: break the connection by moving away before it triggers.

4

Focus her in teamfights to prevent her from shielding her entire team with RE.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026