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Matchup

Lissandra
Lissandra
20%
80%

vs

50.0%
Warwick
Warwick
75%
25%
High sustainHeavy AD damageSustained DPSDive threat

Build vs Warwick

Build adapted to this matchup

Starting items

Doran's Ring
Health Potion
x2

Core build

Dark Seal
1
Malignance
2Mage
Hextech Rocketbelt
3Mage tank

Standard

Sorcerer's Shoes
4Magic pen
Shadowflame
5vs Tank

Summoner spells

41287%
41413%

Anti AD

Plated Steelcaps
4vs AD
Zhonya's Hourglass
5vs AD

Anti Heal

Morellonomicon
6vs Heal

Anti AP

Mercury's Treads
4vs CC
Banshee's Veil
5vs AP

Anti Tank

Shadowflame
5vs Tank
Void Staff
vs Tank
Stormsurge
vs Tank

DPS

Rabadon's Deathcap
Mage
Blackfire Torch
Mage
100.0% WR1 games
DominationDomination
ElectrocuteElectrocute
Cheap ShotCheap Shot
Grisly MementosGrisly Mementos
Ultimate HunterUltimate Hunter
SorcerySorcery
TranscendenceTranscendence
Manaflow BandManaflow Band
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
LissandraLissandra
WarwickWarwick
Neutral
Neutral
Neutral

Warwick's abilities

Passive, spells and ultimate

Eternal Hunger (P)

Warwick's basic attacks deal bonus magic damage. If Warwick is below 50% health, he heals the same amount. If Warwick is below 25% health, this healing triples.

Cooldowns

Cooldowns by spell rank

LevelQWER
38s1m2015s–
67s1m2015s1m50
96s1m1015s1m50
116s1m15s1m30
166s40s13s1m10
186s40s11s1m10

Playing against Warwick

How to counter and exploit weaknesses

1

His R can be blocked by allies — position behind a frontline.

2

Grievous Wounds reduces his massive sustain from Q and passive — buy it early.

3

Warwick is stronger when him or the enemie is low on HP (bonus attack speed and lifesteal) — burst him before he drains.

4

His held Q makes him dash behind you: be careful about your position after a Q.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026