Master Yi vs Locke

Cast Alpha Strike (Q) to dodge a spell or a burst: you're untargetable during the strike, and your autos lower its cooldown.

Cast Meditate (W) to tank a burst mid-teamfight: you take less damage, heal more at low health, and the time left on Highlander (R) is paused.

Activate Highlander (R) to chase: you gain move speed and attack speed, and slows no longer affect you.

Chain kills in teamfights: each takedown lowers the remaining cooldown of your basic spells, and extends Highlander (R) if it's active.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.