Mordekaiser vs Yone

Aim Obliterate (Q) at a lone enemy: if only one enemy is hit, the damage increases.

Hit champions or monsters three times, then stay close: Darkness Rise (passive) then surrounds you with a damage aura and gives you move speed.

Pull your targets into the Obliterate (Q) zone with Death's Grasp (E): each spell that hits also counts toward Darkness Rise (passive).

Cast Indestructible (W) when you're taking damage: it turns stored damage into a shield, and a recast converts part of it into health.

Cast Realm of Death (R) on their carry, or their jungler near an objective: you isolate them with you, steal part of their stats, and keep them if you kill them.

Get out of his line after two Mortal Steel (Q) hits: the next one makes him dash forward and knocks the enemies hit into the air.

During Soul Unbound (E), avoid taking hits: when he snaps back, part of all the damage he dealt you is repeated.

If you have ground-targeted CC, place it on the body he left behind: when Soul Unbound (E) ends, he has to return there.

Judge his threat by his crit items more than his level: Way of the Hunter (passive) raises his critical strike chance, so each crit item does more for him.

In teamfights, don't line up with your allies in front of him: Fate Sealed (R) hits every enemy in a line and knocks them into the air toward him.