Nami vs Locke

Cast Aqua Prison (Q) on a slowed or immobile target, or where they're heading: the bubble lands in an area and stuns every enemy on impact.

Cast Tidecaller's Blessing (E) on your ADC just before they trade: their next autos and abilities slow and deal bonus magic damage.

Cast Ebb and Flow (W) so it bounces from one champion to another: it heals each ally, damages each enemy, and only hits the same champion once.

Cast Tidal Wave (R) to engage or to break an enemy engage: enemies hit take a knock-up and a slow, which lasts longer on those farther away.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.