Matchup

Heavy AD damageSustained DPS

You are stronger late game — farm safe and avoid early trades.

Build vs Twitch

Build adapted to this matchup

Starting items

Doran's Shield
Health Potion

Core build

Sunfire Aegis
1vs AD
Thornmail
2vs Hybride
Unending Despair
3vs AD

Standard

Boots of Swiftness
4vs Slow
Jak'Sho, The Protean
5vs Hybride

Summoner spells

412100%

Anti AD

Plated Steelcaps
4vs AD
Jak'Sho, The Protean
5vs Hybride
Randuin's Omen
vs AD

Anti CC

Mercury's Treads
4vs CC

Other options

Protoplasm Harness
Survival
0.0% WR1 games
SorcerySorcery
Summon AerySummon Aery
Manaflow BandManaflow Band
TranscendenceTranscendence
ScorchScorch
ResolveResolve
Second WindSecond Wind
OvergrowthOvergrowth
Ability HasteHealth ScalingHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
OrnnOrnn
TwitchTwitch
Favorable
Favorable
Passive

Twitch's abilities

Passive, spells and ultimate

Deadly Venom (P)

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

Cooldowns

Cooldowns by spell rank

LevelQWER
316s13s12s
616s13s12s1m30
916s12s12s1m30
1116s11s12s1m30
1616s9s10s1m30
1816s9s8s1m30

Playing against Twitch

How to counter and exploit weaknesses

1

Buy Control Wards: Twitch in Q stealth is an ADC assassin. Control Wards reveal him.

2

Twitch is very squishy and has no mobility — when you spot him, burst him immediately.

3

His R has a limited duration (5s): disengage and wait for R to expire before re-engaging.

4

In lane, respect his invisible cheese at level 2 — ward the bushes and play safe.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026