Pantheon vs Warwick

Start your trades with Shield Vault (W): you leap onto your target and stun them, so Comet Spear (Q) can't miss.

Tap Comet Spear (Q) for a short thrust that refunds part of the cooldown, or hold it to throw your spear farther.

Raise Aegis Assault (E) against enemy burst: you ignore damage from that direction, except from towers.

Roam with Grand Starfall (R): you leap from long range onto the chosen area, and the spell instantly readies Mortal Will (passive).

Keep your health above 50%: below that, Blood Hunt (W) gives him speed toward you and attack speed, three times more below 25%.

When he drops below 50% health, finish him fast, with CC if you have any: Eternal Hunger (passive) then heals him with each auto, three times more below 25%.

If you have a dash, don't count on it to escape his held bite: Jaws of the Beast (Q) makes him follow all your movement, then leap behind you.

In teamfights, stay behind your tankiest allies: Infinite Duress (R) suppresses the first champion hit, and its range grows with his move speed.

If you have Grievous Wounds, apply it to him: his autos heal him at low health, and Infinite Duress (R) heals him for all the damage it deals.