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Matchup

Pyke
Pyke
90%
10%

vs

50.0%
Twitch
Twitch
75%
25%
Heavy AD damageSustained DPS

You are stronger early — look to snowball before your opponent scales.

Build vs Twitch

Build adapted to this matchup

Starting items

Health Potion
x2

Core build

Umbral Glaive
1vs Tank
Voltaic Cyclosword
2vs Tank
Edge of Night
3vs Tank

Standard

Boots of Swiftness
4vs Slow
Youmuu's Ghostblade
5vs Tank

Summoner spells

41495%
344%

Anti AD

Plated Steelcaps
4vs AD
Guardian Angel
5vs AD
Frozen Heart
vs AD
Dead Man's Plate
vs AD
Death's Dance
vs AD

Anti AP

Mercury's Treads
4vs CC
Maw of Malmortius
5vs AP

Anti Tank

Youmuu's Ghostblade
5vs Tank
Axiom Arc
vs Tank
Hubris
vs Tank
Bastionbreaker
vs Tank
Serpent's Fang
vs Tank

DPS

Opportunity
DPS

Other options

Bloodsong
HP
Celestial Opposition
HP
Solstice Sleigh
HP
100.0% WR3 games
DominationDomination
Hail of BladesHail of Blades
Cheap ShotCheap Shot
Sixth SenseSixth Sense
Ultimate HunterUltimate Hunter
ResolveResolve
UnflinchingUnflinching
Bone PlatingBone Plating
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
PykePyke
TwitchTwitch
Aggressive
Neutral
Passive

Twitch's abilities

Passive, spells and ultimate

Deadly Venom (P)

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

Cooldowns

Cooldowns by spell rank

LevelQWER
316s13s12s–
616s13s12s1m30
916s12s12s1m30
1116s11s12s1m30
1616s9s10s1m30
1816s9s8s1m30

Playing against Twitch

How to counter and exploit weaknesses

1

Buy Control Wards: Twitch in Q stealth is an ADC assassin. Control Wards reveal him.

2

Twitch is very squishy and has no mobility — when you spot him, burst him immediately.

3

His R has a limited duration (5s): disengage and wait for R to expire before re-engaging.

4

In lane, respect his invisible cheese at level 2 — ward the bushes and play safe.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026