Senna vs Swain

Attack the souls held by the Mist whenever you can: each soul freed with Absolution (passive) increases your AD, attack range and crit chance.

Fire Piercing Darkness (Q) through an ally or an enemy to hit both: the beam heals your allies, and damages and slows enemies in the line.

Cast Last Embrace (W) on a target that's already slowed or immobilized: after a short delay, they and nearby enemies are rooted.

Cast Curse of the Black Mist (E) to engage or escape with your team: allies who enter it are camouflaged, then fast and unselectable.

Cast Dawning Shadow (R) to save an ally across the map: the beam has unlimited range and shields allies.

Get out of the Nevermove (E) path as it comes back: it only roots on its return to Swain, then he can pull each rooted champion to him.

Leave the area as soon as Vision of Empire (W) appears: it strikes and slows 1.5 seconds later, and each champion hit gives him a Soul Fragment.

During Demonic Ascension (R), back off and hit from range if you can: he only drains nearby enemies, and his form ends when he stops draining.

If you have Grievous Wounds, apply it during Demonic Ascension (R): the drain heals him every second, and that healing keeps him alive.