Senna vs Xerath

Attack the souls held by the Mist whenever you can: each soul freed with Absolution (passive) increases your AD, attack range and crit chance.

Fire Piercing Darkness (Q) through an ally or an enemy to hit both: the beam heals your allies, and damages and slows enemies in the line.

Cast Last Embrace (W) on a target that's already slowed or immobilized: after a short delay, they and nearby enemies are rooted.

Cast Curse of the Black Mist (E) to engage or escape with your team: allies who enter it are camouflaged, then fast and unselectable.

Cast Dawning Shadow (R) to save an ally across the map: the beam has unlimited range and shields allies.

Keep minions between you and Xerath: Shocking Orb (E) stuns the first enemy hit, for longer the farther it has traveled.

Don't stand still, and change direction often: Arcanopulse (Q) hits a target moving forward or backward in a straight line much more easily.

If you can engage, go in while he charges Arcanopulse (Q): he slows down by up to 50%, and he has no dash to escape.

If you have CC and can reach him during Rite of the Arcane (R), use it: he channels the ult, and interrupting it stops his shots.