Matchup

Skarner
Skarner
58%
42%

vs

57.0%

over 128 games

Karthus
Karthus
17%
83%
Heavy AP damageCountered by stasisSustained DPSHigh burst

Favorable matchup

Build vs Karthus

Build adapted to this matchup

Starting items

Mosstomper Seedling

Core build

Heartsteel
1Survival
Thornmail
2vs Hybride
Spirit Visage
3vs AP

Standard

Boots of Swiftness
4vs Slow
Unending Despair
5vs AD

Summoner spells

41199%
6111%

Anti AD

Plated Steelcaps
4vs AD
Unending Despair
5vs AD
Sunfire Aegis
vs AD
Randuin's Omen
vs AD
Knight's Vow
vs AD
Frozen Heart
vs AD

Anti AP

Mercury's Treads
4vs CC
Bandlepipes
5vs Hybride
Kaenic Rookern
vs AP
Force of Nature
vs AP
Hollow Radiance
vs AP

DPS

Titanic Hydra
Bruiser
Trinity Force
DPS

Other options

Protoplasm Harness
Survival
Jak'Sho, The Protean
vs Hybride
Zeke's Convergence
Tank
Sterak's Gage
Survival
Overlord's Bloodmail
HP
100.0% WR2 games
ResolveResolve
Grasp of the UndyingGrasp of the Undying
Shield BashShield Bash
ConditioningConditioning
OvergrowthOvergrowth
InspirationInspiration
Magical FootwearMagical Footwear
Approach VelocityApproach Velocity
Ability HasteHealth ScalingHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
SkarnerSkarner
KarthusKarthus
Neutral
Neutral
Neutral

Karthus's abilities

Passive, spells and ultimate

Death Defied (P)

Upon dying, Karthus enters a spirit form that allows him to continue casting spells.

Cooldowns

Cooldowns by spell rank

LevelQWER
30s15s0.5s
60s15s0.5s3m20
90s15s0.5s3m20
110s15s0.5s3m
160s15s0.5s2m40
180s15s0.5s2m40

Playing against Karthus

How to counter and exploit weaknesses

1

Zhonya's, Edge of Night, and Banshee's block/cancel his R — buy one of these items if Karthus focuses you.

2

His Q deals double damage on isolated targets: stay in your minions or near allies to split the damage.

3

Shields, Soraka R, and heals can counter his R if well-timed — save an emergency heal for Requiem.

4

Karthus is immobile and squishy — dive him quickly to eliminate him before he deals continuous damage.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026