Sylas vs Nasus

Weave an auto after each spell: Petricite Burst (passive) turns it into a chain swing around you, with bonus magic damage.

Save Kingslayer (W) to finish or to save yourself when your health drops: its healing grows with your missing health.

To engage, cast Abscond (E), then recast within 3.5 seconds: Abduct (E) pulls you to the first enemy hit and knocks them into the air.

Cast Hijack (R) on the enemy whose ult can turn a teamfight: you keep a copy of it, cast with your own stats.

Early on, take a trade whenever he steps up to last-hit a minion: each kill with Siphoning Strike (Q) increases its damage for the whole game.

Freeze the wave near your tower: to farm with Siphoning Strike (Q), he then has to step up and expose himself to ganks.

Once he hits level 6, don't engage during Fury of the Sands (R): for 15 seconds, he gains health and resistances, and his area damage scales with your max health.

In teamfights, if you're ranged, hit him while backing off: he has no dash, only Wither (W), a slow that grows stronger over time.