Matchup
Build vs Dr. Mundo
Build adapted to this matchup
Starting items
Core build
Standard
Summoner spells
76%
14%Anti AD
Anti AP
Anti Tank
DPS
Inspiration
First Strike
Magical Footwear
Biscuit Delivery
Cosmic Insight
Sorcery
Transcendence
Manaflow Band
Power Spikes
Strength by game phase
Syndra
Dr. MundoDr. Mundo's abilities
Passive, spells and ultimate
Dr. Mundo resists the first Immobilizing effect that hits him, instead losing Health and dropping a chemical cannister nearby. Dr. Mundo can pick it up by walking over it, restoring Health and reducing this Ability's Cooldown.Dr. Mundo also has significantly increased Health regeneration.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 4s | 17s | 9s | – |
| 6 | 4s | 17s | 9s | 2m |
| 9 | 4s | 16.5s | 9s | 2m |
| 11 | 4s | 16s | 9s | 2m |
| 16 | 4s | 15s | 7.5s | 2m |
| 18 | 4s | 15s | 6s | 2m |
Playing against Dr. Mundo
How to counter and exploit weaknesses
Grievous Wounds is MANDATORY against Mundo — his R regenerates up to 50% of his max HP.
His Q is his only gap-closing tool: dodge it and he can't catch you.
% max HP damage (Vayne W, Kog'Maw, Liandry's) counters him since he stacks HP but few resistances early.
Ignore Mundo in teamfights if possible — focus the carries and kite him, he deals little damage compared to his tankiness.
Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026