Talon vs Warwick

Apply three Blade's End (passive) stacks by hitting with your spells, then strike with an auto: the target starts bleeding and takes heavy damage over time.

Cast Noxian Diplomacy (Q) in melee range when you can: instead of the leap, it lands a critical strike. If it kills, it heals you and comes back faster.

During Shadow Assault (R), break invisibility with an auto or Noxian Diplomacy (Q): the blades then converge on your target instead of coming back to you.

Push your wave, then roam by vaulting walls with Assassin's Path (E): the spell comes back fast, but you can only cross the same wall again after a long delay.

Keep your health above 50%: below that, Blood Hunt (W) gives him speed toward you and attack speed, three times more below 25%.

When he drops below 50% health, finish him fast, with CC if you have any: Eternal Hunger (passive) then heals him with each auto, three times more below 25%.

If you have a dash, don't count on it to escape his held bite: Jaws of the Beast (Q) makes him follow all your movement, then leap behind you.

In teamfights, stay behind your tankiest allies: Infinite Duress (R) suppresses the first champion hit, and its range grows with his move speed.

If you have Grievous Wounds, apply it to him: his autos heal him at low health, and Infinite Duress (R) heals him for all the damage it deals.