Vladimir vs Aurelion Sol

After two Transfusion (Q) casts, the next one is empowered for a few seconds: save it for a trade, since it hits harder and heals you based on your missing health.

Last-hit minions with Transfusion (Q) until your items come in: it deals damage before healing you, and costs you nothing.

Charge Tides of Blood (E) for at least 1 second before releasing: the missiles then also slow, and their damage grows with the charge.

Save Sanguine Pool (W) to dodge CC or a burst: for 2 seconds, you're untargetable. It costs you part of your current health.

Cast Hemoplague (R) before your burst: infected enemies take increased damage from all sources, then the blast heals you for each champion hit.

Stay behind your minions: Breath of Light (Q) hits the first enemy in its path, and only the seconds spent on a champion give him Stardust.

Play hard early and don't let the game drag on: with Cosmic Creator (passive), each of Aurelion Sol's abilities grows permanently stronger through Stardust.

Leave Singularity (E) quickly: it pulls you toward its center, where it executes enemies below a health threshold, and each second inside gives him Stardust.