Vladimir vs Irelia

After two Transfusion (Q) casts, the next one is empowered for a few seconds: save it for a trade, since it hits harder and heals you based on your missing health.

Last-hit minions with Transfusion (Q) until your items come in: it deals damage before healing you, and costs you nothing.

Charge Tides of Blood (E) for at least 1 second before releasing: the missiles then also slow, and their damage grows with the charge.

Save Sanguine Pool (W) to dodge CC or a burst: for 2 seconds, you're untargetable. It costs you part of your current health.

Cast Hemoplague (R) before your burst: infected enemies take increased damage from all sources, then the blast heals you for each champion hit.

Don't stand near your low-health minions: Bladesurge (Q) resets when it kills, so she chains dashes from minion to minion until she reaches you.

As soon as the first blade of Flawless Duet (E) lands, change direction: the stun only hits enemies caught between the two blades.

Take your trades when Ionian Fervor (passive) isn't stacked: she builds stacks with her abilities, and at max stacks her autos deal more damage.

Save your burst for after Defiant Dance (W): while charging, she takes much less damage, but she can't do anything else.

Dodge Vanguard's Edge (R): its blades make you Unsteady, which resets Bladesurge (Q) on you, and the cage they form damages and slows anyone who crosses it.