Matchup

Heavy AP damageCountered by stasisSustained DPSHigh burst

You are stronger late game — farm safe and avoid early trades.

Build vs Karthus

Build adapted to this matchup

Starting items

Health Potion
x2

Core build

Tear of the Goddess
1
Diadem of Songs
2HP
Moonstone Renewer
3HP

Standard

Ionian Boots of Lucidity
4CDR
Dream Maker
5HP

Summoner spells

3780%
31420%

Anti AD

Plated Steelcaps
4vs AD
Knight's Vow
5vs AD

Anti CC

Mercury's Treads
4vs CC

Other options

Dream Maker
HP
Ardent Censer
Mikael's Blessing
HP
Redemption
Dawncore
100.0% WR1 games
SorcerySorcery
Summon AerySummon Aery
Manaflow BandManaflow Band
TranscendenceTranscendence
ScorchScorch
ResolveResolve
RevitalizeRevitalize
Font of LifeFont of Life
Ability HasteAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
YuumiYuumi
KarthusKarthus
Neutral
Neutral
Neutral

Karthus's abilities

Passive, spells and ultimate

Death Defied (P)

Upon dying, Karthus enters a spirit form that allows him to continue casting spells.

Cooldowns

Cooldowns by spell rank

LevelQWER
30s15s0.5s
60s15s0.5s3m20
90s15s0.5s3m20
110s15s0.5s3m
160s15s0.5s2m40
180s15s0.5s2m40

Playing against Karthus

How to counter and exploit weaknesses

1

Zhonya's, Edge of Night, and Banshee's block/cancel his R — buy one of these items if Karthus focuses you.

2

His Q deals double damage on isolated targets: stay in your minions or near allies to split the damage.

3

Shields, Soraka R, and heals can counter his R if well-timed — save an emergency heal for Requiem.

4

Karthus is immobile and squishy — dive him quickly to eliminate him before he deals continuous damage.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026