Matchup
Build vs Senna
Build adapted to this matchup
Starting items
Core build
Standard
Summoner spells
100%Anti AD
Anti CC
Anti Tank
Inspiration
First Strike
Cash Back
Triple Tonic
Jack Of All Trades
Precision
Cut Down
Legend: Haste
Power Spikes
Strength by game phase
Zed
SennaSenna's abilities
Passive, spells and ultimate
When units die near Senna, their souls are periodically trapped by the Black Mist. Senna can attack these souls to free them, absorbing the Mist that held them in death. Mist fuels her Relic Cannon's power with increased Attack Damage, Attack Range, and Critical Strike Chance. Attacks from Senna's Relic Cannon take longer to fire, deal bonus damage, and briefly grant her a portion of her target's Move Speed.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 15s | 11s | 26s | – |
| 6 | 15s | 11s | 26s | 2m20 |
| 9 | 15s | 11s | 26s | 2m20 |
| 11 | 15s | 11s | 26s | 2m |
| 16 | 15s | 11s | 23s | 1m40 |
| 18 | 15s | 11s | 20s | 1m40 |
Playing against Senna
How to counter and exploit weaknesses
Senna scales infinitely with Mist — punish her in lane to prevent her from collecting freely.
Her Q heals but she has to expose herself to use it: punish her positioning when she steps forward to heal.
Her W root has a delay: sidestep it since the projectile is relatively slow.
She's very squishy the entire game: assassins and engages kill her quickly.
Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026