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Matchup

Zoe
Zoe
11%
89%

vs

50.0%
Twitch
Twitch
75%
25%
Heavy AD damageSustained DPS

Build vs Twitch

Build adapted to this matchup

Starting items

Doran's Ring
Health Potion
x2

Core build

Luden's Echo
1Mage
Mejai's Soulstealer
2
Rabadon's Deathcap
3Mage

Standard

Sorcerer's Shoes
4Magic pen
Shadowflame
5vs Tank

Summoner spells

41491%
4216%

Anti AD

Plated Steelcaps
4vs AD
Zhonya's Hourglass
5vs AD

Anti AP

Mercury's Treads
4vs CC
Banshee's Veil
5vs AP

Anti Tank

Shadowflame
5vs Tank
Stormsurge
vs Tank
Void Staff
vs Tank

DPS

Lich Bane
Mage
Horizon Focus
Mage
Hextech Rocketbelt
Mage tank
100.0% WR1 games
DominationDomination
ElectrocuteElectrocute
Sudden ImpactSudden Impact
Grisly MementosGrisly Mementos
Relentless HunterRelentless Hunter
SorcerySorcery
TranscendenceTranscendence
Nimbus CloakNimbus Cloak
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
ZoeZoe
TwitchTwitch
Favorable
Favorable
Passive

Twitch's abilities

Passive, spells and ultimate

Deadly Venom (P)

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

Cooldowns

Cooldowns by spell rank

LevelQWER
316s13s12s–
616s13s12s1m30
916s12s12s1m30
1116s11s12s1m30
1616s9s10s1m30
1816s9s8s1m30

Playing against Twitch

How to counter and exploit weaknesses

1

Buy Control Wards: Twitch in Q stealth is an ADC assassin. Control Wards reveal him.

2

Twitch is very squishy and has no mobility — when you spot him, burst him immediately.

3

His R has a limited duration (5s): disengage and wait for R to expire before re-engaging.

4

In lane, respect his invisible cheese at level 2 — ward the bushes and play safe.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026