Matchup

Heavy AP damageSustained DPSHeavy CC

Build vs Cassiopeia

Build adapted to this matchup

Starting items

Scorchclaw Pup
Health Potion

Core build

Liandry's Torment
1Mage tank
Rylai's Crystal Scepter
2Mage tank
Zhonya's Hourglass
3vs AD

Standard

Sorcerer's Shoes
4Magic pen
Shadowflame
5vs Tank

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Shadowflame
5vs Tank
Bloodletter's Curse
vs Tank

DPS

Rabadon's Deathcap
Mage
Cosmic Drive
Mage tank

Other options

Morellonomicon
vs Heal

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
BrandBrand
CassiopeiaCassiopeia
Favorable
Favorable
Passive

Cassiopeia's abilities

Passive, spells and ultimate

Serpentine Grace (P)

All Move Speed bonuses are more effective on Cassiopeia.

Cooldowns

Cooldowns by spell rank

LevelQWER
33.5s24s0.75s
63.5s24s0.75s2m
93.5s22s0.75s2m
113.5s20s0.75s1m40
163.5s16s0.75s1m20
183.5s16s0.75s1m20

Playing against Cassiopeia

How to counter and exploit weaknesses

1

Turn away when she casts her R: you'll be slowed instead of stunned if you're not facing her.

2

Her DPS depends on landing Q (poison) — if she misses Q, she can't effectively spam E.

3

W prevents dashes: do NOT dash into the zone, go around it.

4

Cassiopeia doesn't have boots — slows are particularly effective against her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026