Diana vs Locke

Hit with Crescent Strike (Q) before Lunar Rush (E): on a target marked with Moonlight, the dash has no cooldown and you can recast it right away.

Weave autos between your spells: after each ability, Moonsilver Blade (passive) boosts your attack speed for 5 seconds, and your third hit cleaves nearby enemies.

Cast Pale Cascade (W) before you engage: you gain a shield, then a second one when the last sphere explodes.

Cast Moonfall (R) in the middle of their team: it pulls in and slows nearby enemies, and hits harder for each champion pulled after the first.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.