Ekko vs Zyra

Throw Timewinder (Q) at a champion, then position so the device passes through them again on its way back: it expands into a slowing field, and the return hits again.

Hit with Timewinder (Q) out and back, and weave in the empowered auto from Phase Dive (E): the third hit triggers Z-Drive Resonance (passive), with bonus damage and speed.

Cast Parallel Convergence (W) where the fight will happen, then step into the sphere when it appears: you stun the enemies inside and gain a shield.

Engage, deal your damage, then cast Chronobreak (R): you return to where you were 4 seconds earlier, in stasis, and recover health based on what you lost.

Get out of the line of Grasping Roots (E): the roots pass through minions and root every enemy hit, then her plants hit the trapped target.

Step on her seeds to destroy them before she grows them: Rampant Growth (W) seeds reveal you for a moment, but leave her no plant.

Take down the plants born from Garden of Thorns (passive), or back off until they die: they take fixed damage, like a ward, and don't live long.

Get out of the Stranglethorns (R) zone as soon as it appears: the vines knock you into the air 2 seconds later, and her plants are empowered inside.

If you can engage, go for Zyra when her plants are far from her: the Thorn Spitter from Deadly Spines (Q) only fires at 575 range.