Fizz vs Locke

Last-hit minions with Seastone Trident (W) early on: if the empowered auto kills, you get mana back and its cooldown drops.

Save Playful (E) to dodge a key spell: you're untargetable for 0.75 seconds, then land with damage and a slow.

Cast Chum the Waters (R) from range: the farther the fish travels before it attaches, the stronger the shark's slow and damage.

After Chum the Waters (R), chain Urchin Strike (Q) and Seastone Trident (W) while the target is slowed: the shark then bursts up under them and knocks them into the air.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.