Matchup

Sustained DPSHeavy AD damageDive threatSplit push

Build vs Vayne

Build adapted to this matchup

Starting items

Scorchclaw Pup

Core build

Dusk and Dawn
1Mage tank
Mejai's Soulstealer
2
Zhonya's Hourglass
3vs AD

Standard

Sorcerer's Shoes
4Magic pen
Nashor's Tooth
5DPS

Summoner spells

411100%

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Shadowflame
5vs Tank
Void Staff
vs Tank
Stormsurge
vs Tank

DPS

Nashor's Tooth
DPS
Rabadon's Deathcap
Mage
Cosmic Drive
Mage tank
100.0% WR1 games
PrecisionPrecision
Press the AttackPress the Attack
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
DominationDomination
Treasure HunterTreasure Hunter
Sudden ImpactSudden Impact
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
FizzFizz
VayneVayne
Aggressive
Neutral
Passive

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026