Matchup

Gangplank
Gangplank
64%
36%

vs

52.9%

over 1216 games

Vayne
Vayne
91%
9%
Sustained DPSHeavy AD damageDive threatSplit push

Skill matchup

Build vs Vayne

Build adapted to this matchup

Starting items

Doran's Blade
Health Potion

Core build

Essence Reaver
1DPS
Infinity Edge
2DPS
The Collector
3vs Tank

Standard

Boots of Swiftness
4vs Slow
Lord Dominik's Regards
5vs Tank

Summoner spells

41479%
41218%

Anti AD

Plated Steelcaps
4vs AD
Death's Dance
5vs AD
Guardian Angel
vs AD
Randuin's Omen
vs AD
Frozen Heart
vs AD

Anti Heal

Mortal Reminder
6vs Hybride

Anti AP

Mercury's Treads
4vs CC
Maw of Malmortius
5vs AP

Anti Tank

Lord Dominik's Regards
5vs Tank
Voltaic Cyclosword
vs Tank
Serpent's Fang
vs Tank
Youmuu's Ghostblade
vs Tank
Hubris
vs Tank
Bastionbreaker
vs Tank
Edge of Night
vs Tank

DPS

Immortal Shieldbow
DPS
Trinity Force
DPS
Liandry's Torment
Mage tank
Endless Hunger
DPS
Spear of Shojin
Bruiser
Malignance
Mage
Hexoptics C44
DPS
Bloodthirster
DPS
Stormrazor
DPS

Other options

Bramble Vest
76.5% WR17 games
SorcerySorcery
Deathfire TouchDeathfire Touch
Nimbus CloakNimbus Cloak
TranscendenceTranscendence
ScorchScorch
PrecisionPrecision
Cut DownCut Down
Legend: HasteLegend: Haste
Adaptive ForceAdaptive ForceHealth

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
GangplankGangplank
VayneVayne
Neutral
Neutral
Neutral

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026