Graves vs Warwick

Position with no minion between you and your target: each New Destiny (passive) auto fires 4 bullets that can't pass through units.

Cast Smoke Screen (W) on their carries: inside the smoke, they're slowed and can't see anything outside it for 4 seconds.

Fire Collateral Damage (R) with your back to the danger: the shot knocks you backward, enough to reposition while dealing damage.

Cast Quickdraw (E) often during your clear: it reloads a shell, gives armor and magic resist, and each bullet that hits lowers its cooldown.

Keep your health above 50%: below that, Blood Hunt (W) gives him speed toward you and attack speed, three times more below 25%.

When he drops below 50% health, finish him fast, with CC if you have any: Eternal Hunger (passive) then heals him with each auto, three times more below 25%.

If you have a dash, don't count on it to escape his held bite: Jaws of the Beast (Q) makes him follow all your movement, then leap behind you.

In teamfights, stay behind your tankiest allies: Infinite Duress (R) suppresses the first champion hit, and its range grows with his move speed.

If you have Grievous Wounds, apply it to him: his autos heal him at low health, and Infinite Duress (R) heals him for all the damage it deals.