Matchup

Sustained DPSHeavy AD damageDive threatSplit push

Build vs Vayne

Build adapted to this matchup

Starting items

Gustwalker Hatchling

Core build

Redemption
1
Mejai's Soulstealer
2
Moonstone Renewer
3HP

Standard

Ionian Boots of Lucidity
4CDR
Echoes of Helia
5HP

Summoner spells

41196%
11124%

Anti CC

Mercury's Treads
4vs CC

DPS

Rylai's Crystal Scepter
Mage tank
Malignance
Mage
Liandry's Torment
Mage tank
Cosmic Drive
Mage tank

Other options

Echoes of Helia
HP
Ardent Censer
Staff of Flowing Water
Dawncore
Shurelya's Battlesong
100.0% WR1 games
SorcerySorcery
Summon AerySummon Aery
Nimbus CloakNimbus Cloak
TranscendenceTranscendence
WaterwalkingWaterwalking
InspirationInspiration
Cash BackCash Back
Cosmic InsightCosmic Insight
Ability HasteMove SpeedHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
IvernIvern
VayneVayne
Favorable
Favorable
Passive

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026