Matchup

Heavy AP damageSustained DPSHeavy CC

Build vs Cassiopeia

Build adapted to this matchup

Starting items

Doran's Blade
Health Potion

Core build

Kraken Slayer
1DPS
Runaan's Hurricane
2DPS
Lord Dominik's Regards
3vs Tank

Standard

Berserker's Greaves
4AS
Hexoptics C44
5DPS

Summoner spells

42180%
4611%

Anti AD

Plated Steelcaps
4vs AD
Guardian Angel
5vs AD

Anti Heal

Mortal Reminder
6vs Hybride

Anti AP

Mercury's Treads
4vs CC
Mercurial Scimitar
5vs AP
Maw of Malmortius
vs AP
Wit's End
vs AP

Anti Tank

The Collector
5vs Tank

DPS

Hexoptics C44
DPS
Infinity Edge
DPS
Phantom Dancer
DPS
Bloodthirster
DPS
Yun Tal Wildarrows
DPS
Stormrazor
DPS
Immortal Shieldbow
DPS
Rapid Firecannon
DPS
100.0% WR3 games
PrecisionPrecision
Lethal TempoLethal Tempo
Presence of MindPresence of Mind
Legend: BloodlineLegend: Bloodline
Cut DownCut Down
InspirationInspiration
Triple TonicTriple Tonic
Cash BackCash Back
Attack SpeedAdaptive ForceHealth

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
JinxJinx
CassiopeiaCassiopeia
Neutral
Neutral
Neutral

Cassiopeia's abilities

Passive, spells and ultimate

Serpentine Grace (P)

All Move Speed bonuses are more effective on Cassiopeia.

Cooldowns

Cooldowns by spell rank

LevelQWER
33.5s24s0.75s
63.5s24s0.75s2m
93.5s22s0.75s2m
113.5s20s0.75s1m40
163.5s16s0.75s1m20
183.5s16s0.75s1m20

Playing against Cassiopeia

How to counter and exploit weaknesses

1

Turn away when she casts her R: you'll be slowed instead of stunned if you're not facing her.

2

Her DPS depends on landing Q (poison) — if she misses Q, she can't effectively spam E.

3

W prevents dashes: do NOT dash into the zone, go around it.

4

Cassiopeia doesn't have boots — slows are particularly effective against her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026