Karthus vs Twitch

Karthus
vs
Not enough games
Twitch
Heavy AD damageSustained DPSHigh burstSplit push

Build vs Twitch

The champion's reference build, for lack of enough games in this matchup

Recommended items for Karthus: Blackfire Torch, Shadowflame, Rabadon's Deathcap, Sorcerer's Shoes, Liandry's Torment, Zhonya's Hourglass, Void Staff, Stormsurge.

Starting items

Scorchclaw Pup
Health Potion

Core build

Blackfire Torch
1
Shadowflame
2
Rabadon's Deathcap
3

Standard

Sorcerer's Shoes
4Magic pen
Liandry's Torment
5

Summoner spells

FlashSmite60%
ExhaustSmite40%

Anti CC

Mercury's Treads
4vs CC

Other options

Liandry's Torment
Zhonya's Hourglass
Void Staff
Stormsurge
Malignance
DominationDomination
Dark HarvestDark Harvest
Cheap ShotCheap Shot
Grisly MementosGrisly Mementos
Ultimate HunterUltimate Hunter
SorcerySorcery
Axiom ArcanistAxiom Arcanist
Gathering StormGathering Storm
Adaptive ForceAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Twitch's abilities

Passive, spells and ultimate

Deadly Venom (P)

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

Cooldowns

Cooldowns by spell rank

LevelQWER
316s13s12s–
616s13s12s1m30
916s12s12s1m30
1116s11s12s1m30
1616s9s10s1m30
1816s9s8s1m30

Playing as Karthus

Tips to maximize your impact

  1. Aim for isolated champions

    Aim Lay Waste (Q) at a champion away from their minions: if the blast hits only one enemy, it deals much more damage.

  2. Wall before your combo

    Place Wall of Pain (W) in their path before your combo: anyone who crosses it is slowed and loses magic resist.

  3. Keep playing after you die

    After you die, keep casting your spells: Death Defied (passive) keeps you in spirit form for a while, and you can still cast Lay Waste (Q) and Requiem (R).

  4. Requiem for the finish

    Save Requiem (R) to finish off wounded enemies, often right after a teamfight: it hits every enemy champion wherever they are, after a 3-second channel.

Playing against Twitch

How to counter and exploit weaknesses

  1. Get out of his cloud fast

    Get out of the Venom Cask (W) cloud fast: it slows you and adds a Deadly Venom stack every second, which powers up his Contaminate (E).

  2. Ward against his ambush

    Ward your brushes and place a Control Ward on his paths: it reveals camouflaged enemies, and Ambush (Q) lets him reach you unseen.

  3. Focus him as soon as he appears

    As soon as he comes out of the Ambush (Q) camouflage, focus him with your allies: he's fragile and has no dash to escape.

  4. Leave his range during his ult

    During Spray and Pray (R), get out of his extended range until the effect ends: his bolts pierce every enemy, so hiding behind an ally won't protect you.

Patch 16.21.1