Twitch vs Karthus
Hard matchup
You are stronger late game. Farm safe and avoid early trades.
Build vs Karthus
Build adapted to this matchup
Recommended items for Twitch: The Collector, Fiendhunter Bolts, Infinity Edge, Berserker's Greaves, Runaan's Hurricane, Lord Dominik's Regards, Yun Tal Wildarrows, B. F. Sword.
Starting items
Core build
Standard
Summoner spells
Anti CC
Other options
Power Spikes
Strength by game phase
Karthus's abilities
Passive, spells and ultimate
Upon dying, Karthus enters a spirit form that allows him to continue casting spells.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 0s | 15s | 0.5s | – |
| 6 | 0s | 15s | 0.5s | 3m20 |
| 9 | 0s | 15s | 0.5s | 3m20 |
| 11 | 0s | 15s | 0.5s | 3m |
| 16 | 0s | 15s | 0.5s | 2m40 |
| 18 | 0s | 15s | 0.5s | 2m40 |
Playing as Twitch
Tips to maximize your impact
- Approach camouflaged
Approach camouflaged with Ambush (Q), then start the fight: when you leave camouflage, you gain bonus attack speed.
- Catch up with Venom Cask
Throw Venom Cask (W) at an enemy fleeing out of your range: the cloud slows them and adds a Deadly Venom (passive) stack every second.
- Poison before you contaminate
Apply as many Deadly Venom (passive) stacks as you can before Contaminate (E): each stack adds damage, and the spell hits every poisoned enemy within 1200 range.
- Shoot through their frontline
During Spray and Pray (R), stay back and aim at their carries through the frontline: your bolts pierce every enemy, with less damage after the first.
- Camouflage again after a kill
When a champion dies poisoned by Deadly Venom (passive), Ambush (Q) comes back right away: recast it to reposition in the middle of the teamfight.
Playing against Karthus
How to counter and exploit weaknesses
- Stay near your minions
Stay near your minions or your allies: Lay Waste (Q) deals much more damage when the blast hits only one enemy.
- Jump on him if you can
If you can engage, jump on him: Karthus has no dash or leap to escape.
- Don't stay low once he hits 6
Once he hits level 6, back instead of staying at low health: Requiem (R) hits every enemy champion wherever they are, 3 seconds after he starts channeling.
- Save your protection for Requiem
If you have a shield, a heal or invulnerability, save it for Requiem (R): it hits every enemy champion 3 seconds after he starts channeling.
- Move away after he dies
Once Karthus is dead, move away: Death Defied (passive) keeps him in spirit form for a while, and he can still cast his spells.
Other Twitch matchups
Patch 16.21.1