Kha'Zix vs Locke

Jump on an isolated target with Leap (E), then Taste Their Fear (Q): with no ally nearby, Unseen Threat (passive) marks them and the spell hits much harder.

In teamfights, cast Void Assault (R) to vanish and reposition: the invisibility triggers Unseen Threat (passive), and your next auto damages and slows.

Detonate Void Spike (W) close to you in the jungle or in teamfights: you heal if you're inside the explosion area.

Pick your evolutions to fit the game: evolved Leap (E) resets on each takedown, evolved Taste Their Fear (Q) gains range and a lower cooldown on isolated targets.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.