Kha'Zix vs Master Yi

Jump on an isolated target with Leap (E), then Taste Their Fear (Q): with no ally nearby, Unseen Threat (passive) marks them and the spell hits much harder.

In teamfights, cast Void Assault (R) to vanish and reposition: the invisibility triggers Unseen Threat (passive), and your next auto damages and slows.

Detonate Void Spike (W) close to you in the jungle or in teamfights: you heal if you're inside the explosion area.

Pick your evolutions to fit the game: evolved Leap (E) resets on each takedown, evolved Taste Their Fear (Q) gains range and a lower cooldown on isolated targets.

Against Highlander (R), don't run alone: regroup with your team, because he gains speed and ignores slows.

If you have CC other than a slow, land it right after Alpha Strike (Q): during the strike, he's untargetable, and Highlander (R) ignores slows.

If you have CC, interrupt Meditate (W): he channels it to heal, more at low health, and to reduce the damage he takes.

Put pressure on his jungle early on: Master Yi is strongest once he has his items, and each stolen camp delays him.