Kog'Maw vs Vayne

Not enough games

Sustained DPSHeavy AD damageSplit pushDive threat

You are stronger late game. Farm safe and avoid early trades.

Build vs Vayne

The champion's reference build, for lack of enough games in this matchup

Starting items

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x2—

Core build

1—

2—

3—

Standard

4Magic pen

5—

Anti CC

4vs CC

Other options

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Strength by game phase

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns by spell rank

Level	Q	W	E	R
3	6s	0s	20s	–
6	4s	0s	20s	1m40
9	2s	0s	20s	1m40
11	2s	0s	20s	1m25
16	2s	0s	16s	1m10
18	2s	0s	12s	1m10

Tips to maximize your impact

Start with Caustic Spittle
Start your trades with Caustic Spittle (Q): it reduces the target's armor and magic resist, and its ranks also give you permanent attack speed.
Activate W before the fight
Activate Bio-Arcane Barrage (W) right before the teamfight: it extends your attack range, and your autos deal damage based on the target's max health.
Slow whoever charges you
When an enemy runs at you, cast Void Ooze (E) between you and them: the trail of ooze slows everyone who crosses it.
Save your R to finish
Save Living Artillery (R) for targets below 40% health, where it deals its max damage: each shot fired in quick succession costs more mana.

How to counter and exploit weaknesses

Don't fight with your back to a wall
Don't stand with your back to a wall against her: Condemn (E) knocks you back, and if you hit terrain, you're stunned.
Short, repeated trades
Take short, repeated trades: she's fragile, and on the third consecutive hit on you, Silver Bolts (W) adds true damage based on your max health.
Don't feed her kills during her ult
During Final Hour (R), back off rather than risk your life: each champion she kills after damaging them extends the effect.

Patch 16.21.1