Locke vs Cassiopeia

Not enough games

Heavy AP damageSustained DPSHeavy pokeHigh burst

You are stronger early. Look to snowball before your opponent scales.

Build vs Cassiopeia

The champion's reference build, for lack of enough games in this matchup

Starting items

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Core build

1—

2—

3—

Standard

4Magic pen

5—

Anti CC

4vs CC

Other options

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Strength by game phase

Passive, spells and ultimate

Serpentine Grace (P)

All Move Speed bonuses are more effective on Cassiopeia.

Cooldowns by spell rank

Level	Q	W	E	R
3	3.5s	24s	0.75s	–
6	3.5s	24s	0.75s	2m
9	3.5s	22s	0.75s	2m
11	3.5s	20s	0.75s	1m40
16	3.5s	16s	0.75s	1m20
18	3.5s	16s	0.75s	1m20

Tips to maximize your impact

Nails first, then Pursuit
Cast Ritual Nails (Q) before Ashen Pursuit (E): your hits consume the nails stuck in the target, and each extra nail adds damage.
Finish them with autos
Finish off wounded targets with autos: Silver Stake (passive) adds magic damage that grows with their missing health.
Activate W as the trade starts
Activate Soul Ignition (W) at the start of a trade: it costs you health, but at the end, you heal back part of the last damage taken, plus more based on your missing health.
Save E for a kill or a gank
Save Ashen Pursuit (E) for a sure kill or to escape a gank: it's your only instant movement, it has a 10-second cooldown, and only a takedown resets it.
Save Purgatory to finish
Save Purgatory (R) to finish: it seals marked enemies below a health threshold, and when you pick up the artifact, each sealed champion raises that threshold for good.

How to counter and exploit weaknesses

Dodge her poison
Dodge Noxious Blast (Q): without poison on you, Twin Fang (E) deals much less damage and doesn't heal her.
Walk around her clouds
Walk around the Miasma (W) clouds: inside, you're slowed and can't use dashes or jumps.
Turn your back on her R
Turn your back to her when she casts Petrifying Gaze (R): facing her, you're stunned; facing away, you're only slowed.

Patch 16.21.1