Miss Fortune vs Xerath

Fire Double Up (Q) at a dying minion in front of a champion: if the shot kills the minion, the bounce onto the champion always crits.

Switch targets often: Love Tap (passive) adds damage on each new target, and lowers the cooldown of Strut (W).

Activate Strut (W) to get in position before Bullet Time (R): you instantly gain its max move speed bonus, plus attack speed.

Cast Bullet Time (R) on enemies who are CC'd or bunched up in a chokepoint: it's a channeled cone, and each wave can crit.

Keep minions between you and Xerath: Shocking Orb (E) stuns the first enemy hit, for longer the farther it has traveled.

Don't stand still, and change direction often: Arcanopulse (Q) hits a target moving forward or backward in a straight line much more easily.

If you can engage, go in while he charges Arcanopulse (Q): he slows down by up to 50%, and he has no dash to escape.

If you have CC and can reach him during Rite of the Arcane (R), use it: he channels the ult, and interrupting it stops his shots.