Miss Fortune

Q (Double Up) bounces to the second target — position yourself so the bounce hits the champion behind the dying minion (guaranteed crit).

R (Bullet Time) deals massive damage in a cone — use it when enemies are CC'd or in a chokepoint.

The passive (Love Tap) deals bonus damage on a new target — alternate between targets when trading to maximize it.

W (Strut) gives movement speed — the first damage taken breaks it. Activate it before positioning for R.

Interrupt her R: it's a channel and she's immobile. A single CC stops it completely.

Don't hide behind low-HP minions: her Q bounces and crits the target behind a dying minion.

Engage in melee: MF is weak up close without her R and depends on range.

Her W speed breaks as soon as she takes damage — a single auto or ability is enough to cancel it.