Mordekaiser vs K'Sante

Aim Obliterate (Q) at a lone enemy: if only one enemy is hit, the damage increases.

Hit champions or monsters three times, then stay close: Darkness Rise (passive) then surrounds you with a damage aura and gives you move speed.

Pull your targets into the Obliterate (Q) zone with Death's Grasp (E): each spell that hits also counts toward Darkness Rise (passive).

Cast Indestructible (W) when you're taking damage: it turns stored damage into a shield, and a recast converts part of it into health.

Cast Realm of Death (R) on their carry, or their jungler near an objective: you isolate them with you, steal part of their stats, and keep them if you kill them.

After two Ntofo Strikes (Q) hit you, back off or dodge the next one: it becomes a shockwave that stuns and pulls.

When he charges Path Maker (W), get out of its line: nothing stops him while he charges, then he rams straight ahead and his dash knocks back and stuns.

Don't fight with your back to a wall when he has All Out (R): if he knocks you into it, you go through, he hits you again and follows, far from your team.

Focus him during All Out (R): he loses max health, bonus armor and bonus magic resist, but heals off his damage, so don't drag it out.