Matchup

Sustained DPSHeavy AD damageDive threatSplit push

Build vs Vayne

Build adapted to this matchup

Starting items

Scorchclaw Pup

Core build

Voltaic Cyclosword
1vs Tank
Axiom Arc
2vs Tank
Edge of Night
3vs Tank

Standard

Ionian Boots of Lucidity
4CDR
Hubris
5vs Tank

Summoner spells

41198%
11142%

Anti AD

Plated Steelcaps
4vs AD
Death's Dance
5vs AD
Guardian Angel
vs AD

Anti AP

Mercury's Treads
4vs CC
Maw of Malmortius
5vs AP

Anti Tank

Hubris
5vs Tank
Serylda's Grudge
vs Tank
Serpent's Fang
vs Tank
Profane Hydra
vs Tank
Black Cleaver
vs Tank
Youmuu's Ghostblade
vs Tank

DPS

Spear of Shojin
Bruiser
Eclipse
DPS
Endless Hunger
DPS
100.0% WR5 games
PrecisionPrecision
ConquerorConqueror
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
InspirationInspiration
Magical FootwearMagical Footwear
Cosmic InsightCosmic Insight
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
NaafiriNaafiri
VayneVayne
Aggressive
Neutral
Passive

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026