Matchup

Strong engageHeavy CCVery tankyHigh sustain

Build vs Zac

Build adapted to this matchup

Starting items

Doran's Shield
Health Potion

Core build

Trinity Force
1DPS
Spirit Visage
2vs AP
Thornmail
3vs Hybride

Standard

Ionian Boots of Lucidity
4CDR
Frozen Heart
5vs AD

Summoner spells

61248%
4630%

Anti AD

Plated Steelcaps
4vs AD
Frozen Heart
5vs AD
Iceborn Gauntlet
vs AD
Dead Man's Plate
vs AD
Randuin's Omen
vs AD
Death's Dance
vs AD

Anti Heal

Chempunk Chainsword
6vs Heal

Anti AP

Mercury's Treads
4vs CC
Force of Nature
5vs AP

DPS

Essence Reaver
DPS
Sundered Sky
Bruiser
Fiendhunter Bolts
DPS

Other options

Jak'Sho, The Protean
vs Hybride
Protoplasm Harness
Survival
Bandlepipes
vs Hybride
100.0% WR3 games
PrecisionPrecision
Fleet FootworkFleet Footwork
TriumphTriumph
Legend: HasteLegend: Haste
Last StandLast Stand
ResolveResolve
UnflinchingUnflinching
Second WindSecond Wind
Ability HasteHealth ScalingHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
NasusNasus
ZacZac
Careful
Careful
Aggressive

Zac's abilities

Passive, spells and ultimate

Cell Division (P)

Each time Zac hits an enemy with an ability, he sheds a chunk of himself that can be reabsorbed to restore Health. Upon taking fatal damage, Zac splits into 4 bloblets that attempt to recombine. If any bloblets remain, he will revive with an amount of Health depending on the Health of the surviving bloblets. Each bloblet has a percentage of Zac's maximum Health, Armor and Magic Resistance. This ability has a 5 minute cooldown.

Cooldowns

Cooldowns by spell rank

LevelQWER
314s5s22s
611s5s22s2m
98s5s22s2m
118s5s22s1m45
168s5s16s1m30
188s5s10s1m30

Playing against Zac

How to counter and exploit weaknesses

1

Walk on his blobs (passive) to destroy them and prevent him from healing.

2

His E is long range but visible and has a windup: side-step when you see him charging.

3

If Zac dies, he splits into blobs that reform: kill all 4 blobs to kill him for good.

4

His engage is strong but he's vulnerable to burst once inside — focus him after his engage.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026