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Matchup

Ryze
Ryze
17%
83%

vs

50.0%
Twitch
Twitch
75%
25%
Heavy AD damageSustained DPS

Build vs Twitch

Build adapted to this matchup

Starting items

Doran's Ring
Health Potion
x2

Core build

Tear of the Goddess
1
Rod of Ages
2HP
Seraph's Embrace
3Mage

Standard

Sorcerer's Shoes
4Magic pen
Actualizer
5Mage

Anti AD

Plated Steelcaps
4vs AD
Zhonya's Hourglass
5vs AD
Frozen Heart
vs AD

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Void Staff
5vs Tank

DPS

Actualizer
Mage
Rabadon's Deathcap
Mage
Cosmic Drive
Mage tank

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
RyzeRyze
TwitchTwitch
Neutral
Neutral
Neutral

Twitch's abilities

Passive, spells and ultimate

Deadly Venom (P)

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

Cooldowns

Cooldowns by spell rank

LevelQWER
316s13s12s–
616s13s12s1m30
916s12s12s1m30
1116s11s12s1m30
1616s9s10s1m30
1816s9s8s1m30

Playing against Twitch

How to counter and exploit weaknesses

1

Buy Control Wards: Twitch in Q stealth is an ADC assassin. Control Wards reveal him.

2

Twitch is very squishy and has no mobility — when you spot him, burst him immediately.

3

His R has a limited duration (5s): disengage and wait for R to expire before re-engaging.

4

In lane, respect his invisible cheese at level 2 — ward the bushes and play safe.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026