Seraphine vs Karthus

Not enough games

High burstHeavy pokeCountered by stasisHeavy AP damage

Build vs Karthus

The champion's reference build, for lack of enough games in this matchup

Starting items

—

x2—

Core build

1—

2—

3—

Standard

4CDR

5—

Anti CC

4vs CC

Other options

—

Strength by game phase

Passive, spells and ultimate

Death Defied (P)

Upon dying, Karthus enters a spirit form that allows him to continue casting spells.

Cooldowns by spell rank

Level	Q	W	E	R
3	0s	15s	0.5s	–
6	0s	15s	0.5s	3m20
9	0s	15s	0.5s	3m20
11	0s	15s	0.5s	3m
16	0s	15s	0.5s	2m40
18	0s	15s	0.5s	2m40

Tips to maximize your impact

Double your Surround Sound
Make Surround Sound (W) your third basic spell: Stage Presence (passive) casts it twice, and the second, cast while shielded, heals your allies.
Beat Drop on a slowed target
Cast Beat Drop (E) on enemies that are already slowed: they're rooted, and those already immobilized are stunned.
Finish with High Note
Save High Note (Q) for a wounded target: its damage grows with the health they've lost.
Send Encore through an ally
Cast Encore (R) through an ally toward the enemies: each champion hit, allies included, extends the spell's range.

How to counter and exploit weaknesses

Stay near your minions
Stay near your minions or your allies: Lay Waste (Q) deals much more damage when the blast hits only one enemy.
Jump on him if you can
If you can engage, jump on him: Karthus has no dash or leap to escape.
Don't stay low once he hits 6
Once he hits level 6, back instead of staying at low health: Requiem (R) hits every enemy champion wherever they are, 3 seconds after he starts channeling.
Save your protection for Requiem
If you have a shield, a heal or invulnerability, save it for Requiem (R): it hits every enemy champion 3 seconds after he starts channeling.
Move away after he dies
Once Karthus is dead, move away: Death Defied (passive) keeps him in spirit form for a while, and he can still cast his spells.

Patch 16.21.1