Matchup

Sion
Sion
63%
37%

vs

48.8%

over 1754 games

Vayne
Vayne
91%
9%
Sustained DPSHeavy AD damageDive threatSplit push

Skill matchup

Build vs Vayne

Build adapted to this matchup

Starting items

Doran's Shield
Health Potion

Core build

Sunfire Aegis
1vs AD
Unending Despair
2vs AD
Thornmail
3vs Hybride

Standard

Boots of Swiftness
4vs Slow
Frozen Heart
5vs AD

Summoner spells

41286%
4146%

Anti AD

Plated Steelcaps
4vs AD
Frozen Heart
5vs AD
Randuin's Omen
vs AD
Dead Man's Plate
vs AD

Anti Heal

Mortal Reminder
6vs Hybride

Anti AP

Mercury's Treads
4vs CC
Jak'Sho, The Protean
5vs Hybride
Hollow Radiance
vs AP
Kaenic Rookern
vs AP
Spirit Visage
vs AP
Force of Nature
vs AP

Anti Tank

Youmuu's Ghostblade
5vs Tank
The Collector
vs Tank
Axiom Arc
vs Tank
Voltaic Cyclosword
vs Tank
Edge of Night
vs Tank
Lord Dominik's Regards
vs Tank
Bastionbreaker
vs Tank

DPS

Titanic Hydra
Bruiser
Liandry's Torment
Mage tank
Infinity Edge
DPS
Sundered Sky
Bruiser

Other options

Overlord's Bloodmail
HP
Heartsteel
Survival
Shurelya's Battlesong
Protoplasm Harness
Survival
69.2% WR13 games
ResolveResolve
Grasp of the UndyingGrasp of the Undying
DemolishDemolish
ConditioningConditioning
OvergrowthOvergrowth
InspirationInspiration
Cash BackCash Back
Approach VelocityApproach Velocity
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
SionSion
VayneVayne
Favorable
Favorable
Passive

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026