Talon vs Locke

Apply three Blade's End (passive) stacks by hitting with your spells, then strike with an auto: the target starts bleeding and takes heavy damage over time.

Cast Noxian Diplomacy (Q) in melee range when you can: instead of the leap, it lands a critical strike. If it kills, it heals you and comes back faster.

During Shadow Assault (R), break invisibility with an auto or Noxian Diplomacy (Q): the blades then converge on your target instead of coming back to you.

Push your wave, then roam by vaulting walls with Assassin's Path (E): the spell comes back fast, but you can only cross the same wall again after a long delay.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.