Matchup

Vayne
Vayne
91%
9%

vs

46.4%

over 1011 games

Nasus
Nasus
54%
46%
Split pushHeavy AD damageSustained DPSVery tanky

Skill matchup

You are stronger late game — farm safe and avoid early trades.

Build vs Nasus

Build adapted to this matchup

Starting items

Doran's Bow
Health Potion
x2

Core build

Blade of The Ruined King
1DPS
Experimental Hexplate
2Bruiser
Trinity Force
3DPS

Standard

Berserker's Greaves
4AS
Guinsoo's Rageblade
5

Summoner spells

4657%
3416%

Anti AD

Plated Steelcaps
4vs AD
Jak'Sho, The Protean
5vs Hybride
Randuin's Omen
vs AD
Guardian Angel
vs AD

Anti Heal

Mortal Reminder
6vs Hybride

Anti AP

Mercury's Treads
4vs CC
Wit's End
5vs AP
Mercurial Scimitar
vs AP

Anti Tank

Terminus
5vs Tank
Lord Dominik's Regards
vs Tank
Hubris
vs Tank
Voltaic Cyclosword
vs Tank
The Collector
vs Tank

DPS

Essence Reaver
DPS
Stormrazor
DPS
Fiendhunter Bolts
DPS
Kraken Slayer
DPS
Infinity Edge
DPS
Phantom Dancer
DPS
Statikk Shiv
DPS
Dusk and Dawn
Mage tank
Hexoptics C44
DPS
Immortal Shieldbow
DPS
Bloodthirster
DPS

Other options

Guinsoo's Rageblade
71.4% WR7 games
PrecisionPrecision
Lethal TempoLethal Tempo
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
ResolveResolve
ConditioningConditioning
OvergrowthOvergrowth
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
VayneVayne
NasusNasus
Neutral
Neutral
Neutral

Nasus's abilities

Passive, spells and ultimate

Soul Eater (P)

Nasus drains his foe's spiritual energy, giving him bonus Life Steal.

Cooldowns

Cooldowns by spell rank

LevelQWER
37.5s15s12s
65.5s15s12s2m
93.5s14s12s2m
113.5s13s12s1m40
163.5s11s12s1m20
183.5s11s12s1m20

Playing against Nasus

How to counter and exploit weaknesses

1

Punish Nasus CONSTANTLY in early game: he is very weak before his stacks and depends on Q farming. Zone him away from minions.

2

Freeze the lane near your tower to prevent him from farming safely — he has to expose himself to ganks.

3

Don't let him free farm: a Nasus with 400+ stacks at 20 minutes is nearly unbeatable in 1v1.

4

Kite him in teamfights: despite his W slow, he's still a melee champion with no real gap-closer.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026