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Matchup

Vayne
Vayne
91%
9%

vs

50.0%
Qiyana
Qiyana
0%
100%
Heavy AD damageHigh burstDive threatCountered by stasis

You are stronger late game — farm safe and avoid early trades.

Build vs Qiyana

Build adapted to this matchup

Starting items

Doran's Blade
Health Potion

Core build

Experimental Hexplate
1Bruiser
Essence Reaver
2DPS
Fiendhunter Bolts
3DPS

Standard

Boots of Swiftness
4vs Slow
Stormrazor
5DPS

Summoner spells

3449%
4637%

Anti AD

Plated Steelcaps
4vs AD
Jak'Sho, The Protean
5vs Hybride
Randuin's Omen
vs AD
Guardian Angel
vs AD

Anti AP

Mercury's Treads
4vs CC
Mercurial Scimitar
5vs AP

Anti Tank

Voltaic Cyclosword
5vs Tank

DPS

Stormrazor
DPS
Trinity Force
DPS
Blade of The Ruined King
DPS
Infinity Edge
DPS
Kraken Slayer
DPS
Phantom Dancer
DPS

Other options

Guinsoo's Rageblade
100.0% WR4 games
PrecisionPrecision
Lethal TempoLethal Tempo
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
ResolveResolve
ConditioningConditioning
OvergrowthOvergrowth
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
VayneVayne
QiyanaQiyana
Passive
Neutral
Aggressive

Qiyana's abilities

Passive, spells and ultimate

Royal Privilege (P)

Qiyana's first basic attack or ability against each enemy deals bonus damage.

Cooldowns

Cooldowns by spell rank

LevelQWER
37s7s11s–
67s7s11s2m
97s7s11s2m
117s7s11s2m
167s7s9s2m
187s7s7s2m

Playing against Qiyana

How to counter and exploit weaknesses

1

Avoid fights near walls and the river: her R stuns against these elements.

2

Her W needs to touch terrain: in the middle of the lane, she has fewer options.

3

Qiyana is squishy and weak early — punish her before level 3 when she gets her combo.

4

If she takes the bush element, watch for the invisibility: control wards reveal her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026